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44+ Synonyms for Illness: Meanings, Uses & Word Choices

synonyms for illness

Quick Answer: The best synonyms for illness include disease, sickness, ailment, disorder, condition, malady, infection, affliction, complaint, and infirmity. Disease is often best for a diagnosed medical problem. Sickness works naturally in everyday conversation, while ailment usually describes a minor health problem. Disorder is suitable for a condition that affects normal physical or mental function. Condition is a neutral and polite choice in formal discussions. Malady, affliction, and infirmity sound more literary or emotional. The best choice among synonyms for illness depends on the cause, seriousness, duration, and context.

Pronunciation and Word Details

Word: Illness.

Pronunciation: /ˈɪl.nəs/

Part of Speech: Noun.

Meaning: A state in which the body or mind is unhealthy or not functioning normally.

US Pronunciation:

UK Pronunciation:

What Does “Illness” Mean?

Illness means a state of poor physical or mental health. It is a noun that can describe a minor health problem, a serious disease, a temporary sickness, or a long lasting medical condition.

The word can refer to the personal experience of feeling unwell. It may include pain, weakness, discomfort, fatigue, emotional difficulty, or reduced ability to complete normal activities.

Illness is often used broadly when the exact disease is unknown, unnecessary, or private.

General Context: She missed several classes because of illness.

Specific Context: His illness was diagnosed as a respiratory infection.

Temporary Context: The brief illness lasted only a few days.

Long Lasting Context: She learned how to manage her chronic illness.

Mental Health Context: Mental illness can affect thoughts, emotions, behavior, and daily functioning.

The word may be countable or uncountable. Use “an illness” when referring to one particular health problem. Use “illness” without an article when discussing poor health in general.

Countable Use: He developed an illness during the trip.

Uncountable Use: Illness prevented her from attending the meeting.

Meaning, Tone, and Context of “Illness”

Illness has a neutral and widely understood tone. It is suitable for casual conversation, formal writing, health discussions, news reports, educational content, workplace communication, and personal messages.

The word is usually less technical than disease, diagnosis, pathology, or disorder. It does not always identify the exact medical cause. Instead, it often focuses on the general state or personal experience of being unwell.

Neutral Use: Illness can describe almost any period of poor health.

Formal Use: The employee requested leave because of illness.

Conversational Use: Her illness kept her at home for several days.

Emotional Use: The family supported him throughout his illness.

Academic Use: The essay examines how illness affects daily life.

Medical Use: The doctor asked when the illness began.

Sensitive Use: Illness can be a respectful choice when a person does not wish to share a diagnosis.

Sickness is often more conversational. Disease sounds more clinical and usually refers to an identifiable medical problem. Condition is neutral and may sound more polite. Ailment usually suggests something less serious.

When and How to Use “Illness”

For General Poor Health

Use illness when the exact medical problem is unknown or does not need to be named.

Example: Her illness prevented her from completing the journey.

For a Diagnosed Health Problem

Illness can refer to a known disease without repeating its specific name.

Example: The treatment helped him manage the illness.

For a Temporary Health Problem

Use illness for a short period of sickness that affects normal activities.

Example: A sudden illness forced her to cancel the appointment.

For a Long Lasting Condition

Illness can describe a chronic condition that continues for months or years.

Example: Living with a long lasting illness required several lifestyle changes.

For Physical Health

Use physical illness when distinguishing bodily health problems from emotional or mental conditions.

Example: The program supports people recovering from physical illness.

For Mental Health

Mental illness refers broadly to health conditions that affect emotions, thoughts, behavior, or functioning.

Example: The course encourages respectful discussions about mental illness.

For Formal Communication

Illness is appropriate in professional messages when personal medical details are unnecessary.

Example: She was absent from work because of illness.

For Compassionate Writing

The word can express concern without sounding overly technical or intrusive.

Example: We were sorry to hear about his recent illness.

Best Synonyms for Illness

Disease

Synonym: A medical problem that affects the normal functioning of the body or mind.

Example: The disease required careful treatment and regular monitoring.

Sickness

Synonym: The condition of being unwell, especially in everyday conversation.

Example: A period of sickness kept her away from work.

Ailment

Synonym: A health problem that is usually minor or not immediately dangerous.

Example: He used the medicine to relieve a common stomach ailment.

Disorder

Synonym: A condition that interrupts normal physical or mental functioning.

Example: The disorder affected her ability to sleep properly.

Condition

Synonym: A neutral term for a particular state of physical or mental health.

Example: His condition improved after several weeks of rest.

Malady

Synonym: An illness or health problem, often used in literary or formal language.

Example: The old remedy was believed to ease the mysterious malady.

Infection

Synonym: An illness caused by harmful organisms entering and multiplying in the body.

Example: The infection caused pain, swelling, and fever.

Affliction

Synonym: A serious or painful illness that causes suffering.

Example: She remained hopeful despite her difficult affliction.

Complaint

Synonym: A health problem or symptom reported by a patient.

Example: Back pain was his most frequent medical complaint.

Infirmity

Synonym: Physical or mental weakness, often associated with age or long lasting illness.

Example: The service assists people affected by age and infirmity.

50 Synonyms for Illness with Short Meanings

  1. Disease: A medical problem that affects normal body or mind function.
  2. Sickness: The general condition of being unwell.
  3. Ailment: A minor or manageable health problem.
  4. Disorder: A condition that disrupts normal physical or mental function.
  5. Condition: A neutral term for a particular health problem.
  6. Malady: An illness, especially in literary or formal language.
  7. Infection: An illness caused by harmful organisms in the body.
  8. Affliction: A painful or serious condition that causes suffering.
  9. Complaint: A reported symptom or health problem.
  10. Infirmity: Physical or mental weakness associated with illness or age.
  11. Indisposition: A mild or temporary state of poor health.
  12. Unwellness: The state of not feeling healthy.
  13. Ill Health: A general state of poor physical or mental health.
  14. Poor Health: A condition in which someone is frequently or seriously unwell.
  15. Health Problem: Any issue that negatively affects health.
  16. Medical Condition: A health problem recognized or treated medically.
  17. Health Condition: A neutral term for an ongoing or temporary health issue.
  18. Medical Problem: A problem involving physical or mental health.
  19. Health Issue: A broad and neutral expression for a health concern.
  20. Medical Complaint: A symptom or problem described to a medical professional.
  21. Syndrome: A recognized group of symptoms that occur together.
  22. Pathology: A disease process or abnormal physical condition in technical language.
  23. Impairment: A reduction in normal physical, mental, or sensory ability.
  24. Debility: Physical weakness caused by illness or poor health.
  25. Weakness: Reduced physical strength or energy.
  26. Frailty: Physical delicacy or weakness, often connected with age or illness.
  27. Malaise: A general feeling of discomfort, weakness, or poor health.
  28. Suffering: Physical or emotional pain caused by illness or difficulty.
  29. Physical Illness: A health problem that primarily affects the body.
  30. Mental Illness: A health condition that affects thoughts, emotions, or behavior.
  31. Chronic Illness: A health problem that continues for a long period.
  32. Acute Illness: A health problem that begins suddenly and may be severe.
  33. Serious Illness: A condition that significantly threatens health or functioning.
  34. Minor Illness: A health problem that is usually mild and temporary.
  35. Short Illness: A brief period of poor health.
  36. Prolonged Illness: A health problem that continues longer than expected.
  37. Infectious Disease: An illness caused by infectious organisms.
  38. Communicable Disease: An illness that can spread between people or organisms.
  39. Noncommunicable Disease: A disease that does not spread directly between people.
  40. Chronic Condition: A medical problem that needs long term care or management.
  41. Acute Condition: A medical problem with a sudden beginning or short course.
  42. Health Disorder: A problem that interferes with normal health or functioning.
  43. Physical Disorder: A condition that affects the body or bodily systems.
  44. Mental Disorder: A condition that affects thinking, mood, behavior, or functioning.
  45. Medical Disorder: A medically recognized disruption of normal function.
  46. Disease Episode: A particular period during which a disease is active.
  47. Bout of Sickness: A limited period of being unwell.
  48. Attack of Illness: A sudden occurrence or worsening of a health problem.
  49. Relapse: The return of an illness after improvement or recovery.
  50. Recurrence: The appearance of an illness again after it has gone away.

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Synonyms for Illness by Context

When Illness Means a General State of Being Unwell

Sickness, unwellness, ill health, poor health, and indisposition describe the general experience of not feeling healthy.

Sickness is common in everyday conversation. Ill health often describes a broader or continuing state. Indisposition is more formal and usually suggests a mild or temporary problem.

Example With Illness: She stayed home because of illness.

Example With Sickness: She stayed home because of sickness.

Example With Indisposition: She was unable to attend because of a temporary indisposition.

When Illness Means a Diagnosed Disease

Disease, disorder, medical condition, syndrome, and pathology are more precise in medical or technical contexts.

Disease usually refers to a recognized medical problem. Disorder focuses on disrupted functioning. Syndrome describes a collection of related symptoms. Pathology is mainly technical.

Example With Illness: The illness affected his breathing.

Example With Disease: The disease affected his breathing.

Example With Disorder: The disorder affected the normal functioning of his lungs.

When Illness Means a Minor Health Problem

Ailment, complaint, indisposition, health issue, and minor illness are appropriate for mild or manageable problems.

Ailment is often used for common problems such as headaches, stomach discomfort, or muscle pain. Complaint may refer to a symptom reported during a medical visit.

Example With Illness: She developed a minor illness during the trip.

Example With Ailment: She developed a minor stomach ailment during the trip.

Example With Complaint: Her main complaint was persistent stomach pain.

When Illness Means a Serious or Painful Condition

Affliction, serious illness, disease, malady, and suffering can emphasize severity or hardship.

Affliction has an emotional tone and highlights suffering. Malady sounds literary or old fashioned. Disease is usually the clearest choice in factual writing.

Example With Illness: He faced the illness with courage.

Example With Affliction: He faced the painful affliction with courage.

Example With Disease: He faced the serious disease with courage.

When Illness Means a Long Lasting Health Problem

Chronic illness, chronic condition, prolonged illness, infirmity, and poor health describe health problems that continue over time.

Chronic condition is neutral and common in formal communication. Infirmity emphasizes weakness or reduced ability.

Example With Illness: She manages her illness through regular care.

Example With Chronic Condition: She manages her chronic condition through regular care.

Example With Infirmity: The facility supports people living with physical infirmity.

When Illness Is Caused by Infection

Infection, infectious disease, and communicable disease are suitable only when the cause or method of spread is relevant.

Do not use infection as a replacement for every illness. Many illnesses are not caused by infectious organisms.

Example With Illness: The illness spread quickly through the group.

Example With Infection: The infection spread quickly through the group.

Example With Communicable Disease: Officials worked to limit the spread of the communicable disease.

Another Word for Illness

The best single replacement for illness is often sickness because both words can describe the general state of being unwell. However, disease is better when referring to a diagnosed medical problem, ailment suits a minor problem, and condition offers a neutral or polite alternative.

Original: Her illness lasted for several days.

Better Option: Her sickness lasted for several days.

Original: Researchers are studying the causes of the illness.

Better Option: Researchers are studying the causes of the disease.

Original: He visited the clinic for a minor illness.

Better Option: He visited the clinic for a minor ailment.

Original: She receives regular treatment for her illness.

Better Option: She receives regular treatment for her medical condition.

The strongest alternative depends on whether the sentence emphasizes symptoms, diagnosis, severity, duration, cause, or personal experience.

When Not to Use “Illness”

Avoid illness when a more precise word would make the meaning clearer. The word may sound vague when the diagnosis, symptom, cause, or type of condition is already known.

When the Exact Disease Is Important

Use the specific disease name or the word disease when medical accuracy matters.

Weak: The study examines an illness that affects blood sugar control.

Better: The study examines a disease that affects blood sugar control.

When Referring Only to a Symptom

A symptom is evidence of a health problem, not the illness itself.

Weak: Her main illness was a severe headache.

Better: Her main symptom was a severe headache.

When the Problem Is a Minor Complaint

Ailment or complaint may sound more proportionate than illness.

Weak: He has a small illness in his shoulder.

Better: He has a minor shoulder ailment.

When Referring to an Infection

Use infection when the sentence specifically discusses an infectious cause.

Weak: The wound developed an illness.

Better: The wound developed an infection.

When Discussing Normal Recovery

Recovery or healing may be clearer when the focus is improvement rather than poor health.

Weak: Her illness became better each day.

Better: Her condition improved each day.

When Repetition Makes Writing Dull

Replace repeated uses of illness with accurate alternatives.

Weak: The illness was serious, and the illness required treatment because the illness affected his breathing.

Better: The disease was serious and required treatment because the condition affected his breathing.

Words Commonly Confused With Illness

Illness vs Disease: Illness describes the experience or state of being unwell. Disease usually refers to an identifiable medical problem with recognized characteristics.

Illness vs Sickness: Both can mean being unwell. Illness is slightly more neutral and formal, while sickness is common in everyday speech and may also refer to nausea.

Illness vs Ailment: Illness can be mild or serious. Ailment usually suggests a minor, limited, or manageable health problem.

Illness vs Disorder: Illness is broad. Disorder describes a disruption in normal physical or mental functioning and is often part of a formal diagnosis.

Illness vs Condition: Illness directly suggests poor health. Condition is more neutral and may describe a temporary, chronic, mild, or serious medical state.

Illness vs Symptom: Illness is the overall health problem. A symptom is a sign or experience produced by that problem, such as pain, coughing, or fatigue.

Illness vs Infection: Illness can have many causes. Infection specifically involves harmful organisms entering and multiplying within the body.

Illness vs Syndrome: Illness is a broad health state. Syndrome is a recognizable group of signs and symptoms that occur together.

Illness vs Disability: Illness refers to poor health. Disability refers to an impairment that may affect activities or participation and is not automatically the same as illness.

Illness vs Malaise: Illness is a health problem or state. Malaise is a general feeling of discomfort or weakness that may occur during an illness.

Which Synonym Should You Choose?

Choose disease when discussing a diagnosed medical problem, its causes, treatment, or prevention.

Choose sickness for natural everyday conversation about feeling unwell or being absent.

Choose ailment for a minor, common, or manageable health problem.

Choose disorder when describing disrupted physical, mental, emotional, or behavioral functioning.

Choose condition when you need a neutral, respectful, or professional term.

Choose infection when the health problem is specifically caused by infectious organisms.

Choose complaint when discussing a symptom or problem reported by a patient.

Choose affliction when emphasizing pain, suffering, or emotional hardship.

Choose infirmity when describing physical weakness connected with illness, disability, or age.

Choose indisposition when referring politely to a mild or temporary period of poor health.

Choose syndrome when describing a recognized collection of symptoms.

Choose pathology in technical or academic discussions about disease processes.

Choose chronic illness when the problem continues for a long period.

Choose acute illness when the condition begins suddenly or develops quickly.

Choose relapse when an illness returns after a period of improvement.

Choose recurrence when a condition appears again after it was previously absent.

Real Life Examples of “Illness” in Sentences

Original: Her illness prevented her from attending the family event.

Better Option: Her sickness prevented her from attending the family event.

Original: The illness requires regular medical care.

Better Option: The condition requires regular medical care.

Original: Researchers are trying to understand the illness.

Better Option: Researchers are trying to understand the disease.

Original: He developed a minor illness while traveling.

Better Option: He developed a minor ailment while traveling.

Original: The illness affected her ability to concentrate.

Better Option: The disorder affected her ability to concentrate.

Original: The illness was caused by bacteria entering the wound.

Better Option: The infection was caused by bacteria entering the wound.

Original: She endured the painful illness with great courage.

Better Option: She endured the painful affliction with great courage.

Original: His illness returned several months after treatment.

Better Option: His condition relapsed several months after treatment.

Original: The doctor asked him to describe his illness.

Better Option: The doctor asked him to describe his medical complaint.

Original: Years of illness had reduced his physical strength.

Better Option: Years of poor health had caused significant debility.

Synonym Groups and Usage Differences

General Health Group

Sickness, unwellness, ill health, poor health, and health issue describe being unhealthy without necessarily naming a diagnosis. These words work well in general conversation and broad explanations.

Example: A period of sickness kept him away from his usual activities.

Medical Diagnosis Group

Disease, disorder, medical condition, syndrome, and pathology are more precise. They are useful in medical, scientific, academic, and formal writing.

Example: The disorder interferes with the body’s normal ability to process nutrients.

Minor Problem Group

Ailment, complaint, indisposition, and minor illness suggest a problem that is limited, temporary, or less serious.

Example: She recovered quickly from the minor ailment.

Serious Suffering Group

Affliction, malady, serious illness, and suffering emphasize pain, hardship, or severity. Affliction and malady can sound more emotional or literary.

Example: The community offered support during his difficult affliction.

Weakness Group

Infirmity, debility, frailty, weakness, and impairment focus on reduced strength or ability rather than the disease itself.

Example: The illness caused weakness and physical debility.

Duration Group

Acute illness, chronic illness, prolonged illness, relapse, and recurrence describe how a condition begins, continues, returns, or changes over time.

Example: The chronic illness requires continuing care.

Infectious Group

Infection, infectious disease, and communicable disease are appropriate when harmful organisms or transmission are important to the meaning.

Example: The infection responded well to treatment.

Mental Health Group

Mental illness, mental disorder, condition, and impairment may be used when discussing health problems that affect thoughts, mood, emotions, behavior, or daily functioning.

Example: The organization provides practical support for people managing mental illness.

Antonyms of Illness

The opposite of illness depends on whether the sentence refers to health, strength, recovery, or normal functioning.

Health: The state of being physically or mentally well.

Wellness: An active state of overall physical and mental well being.

Good Health: A condition in which the body and mind function effectively.

Fitness: Physical strength and the ability to perform activities.

Strength: Physical or emotional power and resilience.

Vitality: Energy, liveliness, and healthy activity.

Recovery: The process of becoming healthy again after illness.

Healing: The process through which the body or mind improves.

Soundness: A healthy and stable condition.

Wholeness: A complete state of physical, emotional, or mental well being.

Normal Functioning: The healthy operation of the body or mind.

Robustness: Strong health and resistance to weakness.

Resilience: The ability to recover from illness or difficulty.

Improvement: A change toward a healthier condition.

Remission: A period in which signs or symptoms of an illness decrease or disappear.

Comparison: Illness vs Related Words

Illness vs Disease

Illness describes the state or personal experience of being unwell. Disease refers more specifically to a recognized medical problem.

Example With Illness: Her illness made everyday activities difficult.

Example With Disease: The disease affects the nervous system.

Illness vs Sickness

Illness is neutral and suitable for most formal or general situations. Sickness is more conversational and may also describe nausea.

Example With Illness: His illness required several weeks of rest.

Example With Sickness: A sudden sickness kept him in bed all weekend.

Illness vs Ailment

Illness may be minor, moderate, or serious. Ailment generally suggests a smaller or less dangerous health problem.

Example With Illness: She was treated for a serious illness.

Example With Ailment: She used a simple remedy for a minor ailment.

Illness vs Disorder

Illness focuses on poor health or the experience of being unwell. Disorder focuses on abnormal or disrupted functioning.

Example With Illness: The illness caused tiredness and discomfort.

Example With Disorder: The sleep disorder prevented him from resting properly.

Illness vs Condition

Illness clearly indicates that someone is unhealthy. Condition is broader, more neutral, and often preferred when discussing an ongoing medical situation.

Example With Illness: Her illness became worse during the winter.

Example With Condition: Her condition requires regular monitoring.

Illness vs Infection

Illness is a broad term that can have many causes. Infection specifically refers to harmful organisms affecting the body.

Example With Illness: The illness caused fever and weakness.

Example With Infection: The infection developed after the injury.

Illness vs Symptom

Illness is the complete health problem. A symptom is one effect or sign of that problem.

Example With Illness: The illness lasted for two weeks.

Example With Symptom: Coughing was the first symptom she noticed.

Illness vs Affliction

Illness is neutral and factual. Affliction emphasizes suffering, difficulty, or emotional hardship.

Example With Illness: He received treatment for the illness.

Example With Affliction: He faced the painful affliction with patience.

Common Phrases and Expressions With Illness

Serious Illness: A health problem that presents significant danger or disruption.

Chronic Illness: A condition that continues for a long time.

Acute Illness: A condition that begins suddenly and may develop quickly.

Mental Illness: A health condition that affects thoughts, emotions, behavior, or functioning.

Physical Illness: A health problem that primarily affects the body.

Sudden Illness: A health problem that begins unexpectedly.

Brief Illness: A short period of being unwell.

Prolonged Illness: A health problem that continues for an extended period.

Terminal Illness: A serious condition that is expected to shorten a person’s life.

Childhood Illness: A disease or health problem commonly experienced during childhood.

Recover From Illness: To become healthy again after being unwell.

Struggle With Illness: To experience ongoing difficulty because of poor health.

Prevent Illness: To reduce the chance that a health problem will develop.

Treat an Illness: To provide care intended to control, reduce, or remove a health problem.

History of Illness: A record of previous health problems.

Common Mistakes to Avoid

Using Illness for Every Medical Meaning

Illness is broad, but disease, infection, disorder, symptom, and condition have more specific meanings. Choose the term that accurately describes the situation.

Incorrect: A cough is a common illness.

Correct: A cough is a common symptom.

Confusing Illness With Disease

A person can feel ill without having a confirmed disease. A disease can also be present before a person feels unwell.

Weak: The test identified the exact illness.

Better: The test identified the exact disease.

Using Infection Without Evidence of an Infectious Cause

Not every illness is an infection. Use infection only when an infectious cause is part of the meaning.

Incorrect: Stress caused an infection.

Correct: Stress contributed to her poor health.

Describing a Minor Problem Too Dramatically

Affliction and serious illness may sound too strong for a small or temporary problem.

Weak: He suffered a terrible affliction in his finger.

Better: He developed a minor finger ailment.

Repeating Illness Too Often

Repeated wording can make a paragraph sound dull or unclear. Replace illness with disease, condition, ailment, infection, or another precise alternative when appropriate.

Weak: The illness began suddenly, and the illness caused pain before the illness improved.

Better: The condition began suddenly, caused pain, and improved after treatment.

Using Ill Instead of Illness

Ill is usually an adjective. Illness is a noun.

Incorrect: Her ill lasted several days.

Correct: Her illness lasted several days.

Correct: She was ill for several days.

Forgetting the Article Before a Countable Use

Use “an” when illness refers to one specific health problem.

Incorrect: He developed illness during the journey.

Correct: He developed an illness during the journey.

When illness refers to poor health in general, an article may not be necessary.

Correct: Illness can affect a person’s daily routine.

Using Unnatural Combinations

Some phrases sound awkward even when their individual words are grammatically correct.

Weak: He caught a chronic illness yesterday.

Better: He was diagnosed with a chronic illness.

Better: He caught an infectious illness during the trip.

Replacing Illness With a Word That Changes the Meaning

A symptom, disability, weakness, and illness are related but not interchangeable in every sentence.

Weak: Her disability lasted for three days and caused a fever.

Better: Her illness lasted for three days and caused a fever.

Conclusion

The most useful synonyms for illness include disease, sickness, ailment, disorder, condition, infection, affliction, complaint, and infirmity. Choose disease for a diagnosed medical problem, sickness for everyday speech, ailment for a minor concern, and condition for neutral or formal writing. Disorder emphasizes disrupted functioning, while infection identifies a particular cause. Understanding these differences helps you discuss physical and mental health clearly, respectfully, and accurately. The best synonym always depends on the seriousness, cause, duration, and purpose of the sentence.

FAQs About Synonyms for Illness

What Is the Best Synonym for Illness?

Sickness is the closest general synonym. Disease is better for a diagnosed medical problem, while condition is a neutral and professional alternative.

Is Disease the Same as Illness?

Not exactly. Disease usually refers to an identifiable medical problem. Illness can describe the personal experience or general state of being unwell.

What Is a Formal Word for Illness?

Medical condition, disorder, disease, and infirmity are formal alternatives. The best choice depends on the exact health situation.

What Is a Mild Synonym for Illness?

Ailment and indisposition are useful for mild or temporary health problems. Minor illness is also clear and natural.

What Is a Polite Alternative to Illness?

Condition or health condition often sounds neutral and respectful, especially when personal medical details are private.

Can Infection Replace Illness?

Only when the illness is caused by infectious organisms. Infection should not replace illness when the cause is unknown or noninfectious.

What Is the Difference Between Sickness and Illness?

Both describe being unwell. Sickness is more common in casual speech and can also refer to nausea. Illness is broader and slightly more formal.

I am Rachel T. Morgan, the author of Synonympedia.com. I create detailed word guides for readers who want to understand synonyms beyond simple lists. My writing focuses on meaning, tone, grammar use, antonyms, examples, and comparisons so readers can use words with more confidence.

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